Enhanced production of unstable polymorph by antisolvent crystallization supplying minute-bubbles
نویسندگان
چکیده
منابع مشابه
Enhanced production of unstable polymorph by antisolvent crystallization supplying minute-bubbles
Differences in physical and chemical properties between polymorphic compounds (e.g. solubility, dissolution rate, chemical reactivity, resistance to degradation, bioavailability) are highly significant for the pharmaceutical industry, which requires effective methods to control polymorphism of organic crystals [1, 2]. In particular, to improve the functionality such as solubility or bioavailabi...
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Crystallization plays an important role in separation and purification of the antibiotics. And it is also an indispensable step in preparation of pharmaceuticals with biological activities and specific crystal form. As the last step in purification, crystallization determines the puri‐ ty, crystal habit, granularity and its distribution as well as pharmacologic effect, biologic ac‐ tivity and p...
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ژورنال
عنوان ژورنال: MATEC Web of Conferences
سال: 2013
ISSN: 2261-236X
DOI: 10.1051/matecconf/20130301056